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Menambahkan:1002, Huanmao Bangunan, No.105, Mengcheng Jalan, Hefei Kota, 230061, Cina
Nomor CAS:879085-55-9
Rumus Molekul: C19H14Cl2N2O3S
Berat Molekul: 421,3
TIDAK EINECS: 806-752-3
Nomor MDL: MFCD12407408
Deskripsi Produk:
Nama Produk:Vismodegib CAS 879085-55-9
Sinonim:
2-Kloro-N-[4-kloro-3-(2-piridinil)fenil]-4-(metilsulfonil)benzamid;BROMO-1-NAPHTA
BenzaMida, 2-kloro-N-[4-kloro-3-(2-piridinil)fenil]-4-(Metilsulfonil)-;
VisModegib (GDC-0449);
Sifat Kimia & Fisika
Penampilan: Putih sampai Putih Padat
Pengujian: 99%+
Titik didih:561,6±50,0 derajat
Titik Leleh:179-181 derajat
Berat Molekul:421.3
Kepadatan:1.440
Pka:10,72±0,70
Stabilitas:Stabil selama 2 tahun sejak tanggal pembelian sesuai persediaan. Larutan dalam DMSO atau etanol dapat disimpan pada suhu -20 derajat hingga 3 bulan.
Aplikasi:
Vimodej targets SMO protein and inhibits Gli activation, thereby inhibiting downstream gene transcription and expression.For the treatment of locally progressive or metastatic basal cell carcinoma in adults who have recurred after surgery or are not well treated with surgery or radiotherapy; One of the most common skin cancers is basal cell carcinoma (BCC), which originates in the surface layer of the skin and does not cause pain to patients. The risk was greatest for skin diseases that were regularly exposed to the sun or ultraviolet light. The development and listing of Vimedji has brought good news to patients with BCC, and its clinical role is important and the target market is huge, and it has to grow into a "giant bomb" class (>$1 miliar) obat di masa depan.
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